POPSO CAS 68189-43-5
PRODUCT NAME: 1,4-Piperazinebis(2-hydroxy-1-propanesulfonic acid)(POPSO)
CAS: 68189-43-5
PURITY: 99%
APPEARANCE: White crystalline powder
USAGE: Biological buffer
SHELF TIME: 12 Months
Description
About POPSO cas 68189-43-5
1. Capacity:
About 300 tons a year, in current stock.
2. Properties:
The POPSO is white crystalline powder.
Easy to absorb moisture.
Soluble in water.
3. Usages:
Biological buffer.
POPSO details

Basic information
| Name: | POPSO |
| MF: | C10H22N2O8S2 |
| MW: | 362.42 |
| CAS: | 68189-43-5 |

Appearance
White crystalline powder
Note:
High hygroscopicity

Packages
1kg/25kg/100kg/bag/drum

shippment
By sea/ By express/ By air
Product Quality Standard
Chemiccal properties:
| Melting point | 320°C |
| density | 1.578±0.06 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | 1 M NaOH: 0.1 M, clear, colorless |
| form | Solid |
| color | White powder |
| PH Range | 7.2 - 8.5 |
| pka | 7.8(at 25℃) |
| PH | 7.2-8.5 |
Specification Sheet:
| Test | Specification |
| Appearance (Color) | White |
| Appearance (Form) | Crystalline Powder |
| Solubility (Color) | Colorless |
|
Solubility (Turbidity) at 10 g plus 40 ml of 1N NaOH |
Clear to Slightly Hazy |
| Infrared spectrum | Conforms to Structure |
| Water (by Karl Fischer) | ≤ 10 % |
|
A290 UV absorbance (20% W/W) in NaOH |
≤ 0.1 |
| Heavy Metals | ≤ 5 ppm |
|
Purity (Titr. by NAOH) anhydrous |
≥ 99 % |
Advantages
1. Moderate buffer range
pH range: 7.2-8.5
POPSO's buffer range is suitable for many biological experiments, especially under neutral to weakly alkaline conditions (such as cell culture, enzyme reactions, etc.).
Compared with some common buffers (such as Tris, HEPES), POPSO is more stable under weakly alkaline conditions.
2. Low cytotoxicity
POPSO has low toxicity to cells and is suitable for cell culture and biological experiments.
POPSO has less interference with cell growth and metabolism than some buffers, such as phosphate buffers.
3. Chemical stability
POPSO is chemically stable at room temperature and is not easy to decompose.
POPSO is more reliable under experimental conditions than some buffers that are susceptible to temperature or light, such as Tris.
4. Low affinity for metal ions
POPSO has a weak binding ability to metal ions and is suitable for experiments involving metal ions (such as enzyme activity studies).
Compared with chelating agents such as EDTA or citrate, POPSO does not significantly interfere with the activity of metal ions.
5. Good solubility
POPSO is easily soluble in water and is easy to prepare buffer solutions.
Compared to some buffers with lower solubility (such as MOPS), POPSO is easier to prepare high concentration solutions.
6. Low UV absorption
POPSO has low absorption in the UV region and is suitable for experiments that require UV detection (such as protein or nucleic acid analysis).
Compared with some high UV absorbent buffers (such as Tris), POPSO does not interfere with the experimental results.
Products Usages
usages of POPSO CAS 68189-43-5
Biological buffer series products from Shandong Sparrow Chemical CO.,LTD
biological buffer
usage
Cell culture
POPSO is used to maintain the pH stability of cell media, especially under weakly alkaline conditions (pH 7.2-8.5), suitable for the growth of certain specific cell lines.
Enzymatic research
In the enzyme reaction system, POPSO, as a buffer, can maintain the pH stability of the reaction system and ensure the optimal conditions for enzyme activity.
Protein purification and analysis
POPSO is used as a buffer system during protein purification to prevent protein denaturation or degradation.
Due to its low UV absorption properties, POPSO is also suitable for UV detection analysis of proteins or nucleic acids.
Molecular biology experiment
In PCR, nucleic acid extraction and enzyme digestion reactions, POPSO can be used as buffer to maintain the pH stability of the reaction system.
Biochemical research
POPSO is used to study biomolecular interactions (such as protein-ligand binding, enzyme kinetics, etc.), providing a stable experimental environment.
principle of action
pH buffering
POPSO is a zwitterionic buffer whose molecules contain multiple protonated and deprotonated groups (such as hydroxyl, sulfonic, and piperazine rings).
In solution, POPSO is able to resist changes in pH by accepting or releasing protons (H +), maintaining the pH stability of the system.
Buffer range
With an effective buffer range of pH 7.2-8.5 and a pKa value close to 7.8, POPSO is particularly suitable for use in neutral to weakly alkaline conditions.
Low interference
POPSO has a low affinity for metal ions and does not significantly interfere with enzyme activity or biomolecular function.
Its low UV absorption makes it suitable for experiments requiring UV detection to avoid background interference.
Biocompatibility
POPSO is less toxic to cells and biomolecules and is able to maintain the pH stability of the system without affecting the biological activity.

Related Product Introduction
Shandong Sparrow Chemical Company was established in 2007, focusing on the research and development, production and sales of pharmaceutical intermediates and chemical raw materials. The company's products are widely used in pharmaceutical, fine chemical and other industries.
With advanced production technology, strict quality management system and professional research and development team, we are committed to providing customers with high quality products and customized solutions. Adhering to the concept of "innovation, environmental protection and sustainable development", the company continues to promote industry progress and create value with global partners.

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Products Shipment
Shipment

01
International express

02
By sea

03
By air

04
By railway
How to start order?
Contact information:
Melanie Yin
Phone: +8615662727073
Email: export012@sparrowchemical.com
WhatsApp:+8618363408350

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