CAS 65294-16-8 Medical Grade Perfluoro-(2,5,8-trimethyl-3,6,9-trioxadodecanoic)acid
Chemical structure and properties CAS 65294-16-8 Molecular Formula C12HF23O5 Appearance Generally a white or off-white powdery solid. Density Approximately 1.7 g/cm³ Molecular Structure It is formed by the tetramerization of hexafluoropropylene oxide (HFPO). The molecule contains three...
Description
Chemical structure and properties
CAS
65294-16-8
Molecular Formula
C12HF23O5
Appearance
Generally transparency liquid.
Density
Approximately 1.7 g/cm³
Molecular Structure
It is formed by the tetramerization of hexafluoropropylene oxide (HFPO). The molecule contains three ether bonds (-O-) and one carboxyl group (-COOH), and belongs to the class of short-chain perfluoroalkyl ether carboxylic acids (PFECA).
Physicochemical Properties
Easily soluble in polar organic solvents (such as methanol, DMSO), with extremely low surface energy (approximately 15 mN/m) and excellent hydrophobic and oleophobic properties.
It has high chemical stability and is resistant to strong acids, strong alkalis and high-temperature environments.
Purity Standards
The purity of medical-grade is ≥ 99.5% (tested by HPLC), with strict control over impurity content:
Heavy metals (Pb, Cd, Hg): ≤ 0.1 ppm;
Residual solvents (methanol, acetone): ≤ 500 ppm;
Moisture content: ≤ 0.1%.
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Medical-Grade Application Fields
Surface Modification of Medical Devices
Anticoagulant Coatings: Grafted onto the surface of cardiovascular stents, artificial blood vessels, and other devices via covalent bonds, reducing platelet adhesion rate (by 40%) and significantly lowering the risk of thrombosis.
Lubricating Coatings: Applied to catheters, endoscopes, and similar instruments, reducing the friction coefficient by 30-50%, improving operational smoothness, and minimizing tissue damage.
Antifouling Coatings: Prevent the adhesion of biofilms (such as bacteria and proteins), extending the service life of devices and reducing the risk of infection (e.g., dental implants).
Biomedical Materials
Blended with biodegradable materials such as polylactic acid (PLA) and polyethylene glycol (PEG) to fabricate tissue engineering scaffolds, regulating cell adhesion and proliferation (with osteoblast activity increased by 25%).
Used for surface modification of dental implants, enhancing osseointegration strength by 30% and reducing the expression of inflammatory factors (IL-6, TNF-α) by 50%.
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