Raw Material For Type 2 Diabetes Medication 3-Amino-1-adamantanol Cas No.702-82-9
3-Amino-1-adamantanol is a high-purity, crystalline compound that combines an adamantane backbone with amino and hydroxyl functional groups. This unique structure makes it valuable in applications across pharmaceuticals, materials science, and organic synthesis. Known for its stability and precise reactivity, 3-Amino-1-adamantanol is essential for advanced chemical processes.
Description
3-Amino-1-adamantanol (also known as 3-amino-1-hydroxyadamantane) is a key pharmaceutical intermediate, primarily serving as a raw material for the type 2 diabetes drug vildagliptin.Shandong Sparrow Chemical Co., Ltd. This is a top-quality supplier of this product !
Product Information
| Item | Details |
|---|---|
| Chemical Identification | CAS Number: 702-82-9; EINECS Number: 615-098-6; |
| Molecular Basics | Molecular Formula: C₁₀H₁₇NO; Molecular Weight: 167.25 |
| Physical Appearance | White to off-white crystalline powder at 20℃ |
| Key Physical Properties | Melting point: 265 - 271℃ (decomposes during melting); Boiling point: Approximately 266.8℃ at 760 mmHg; Density: About 1.252 g/cm³. It is slightly soluble in methanol and DMSO, and insoluble in water. The vapor pressure is 0.00115 mmHg at 25℃. |
| Storage Requirements | It is recommended to store it in a cool place with a temperature below 15℃, protected from light and sealed properly, to prevent moisture absorption, strong light exposure or high temperature effects. |
Core Pharmaceutical Application
Its most important application lies in being the core intermediate of synthetic vildagliptin, which is widely used as a DPP-4 inhibitor for treating type 2 diabetes. Vildagliptin regulates blood sugar levels by promoting insulin secretion and reducing glucagon release. The amino and hydroxyl functional groups in the 3-amino-1-decanol molecule structure can enable precise chemical reactions, which are crucial for constructing the active structure of vildagliptin. With the increasing number of global patients with type 2 diabetes, the demand for this intermediate remains strong. Moreover, due to its good chemical stability and pharmacological activity, it may also be used to develop other drugs based on decanols.
About Us
Shandong Sparrow Chemical Co., Ltd. was established in 2017, is a collection of organophosphine compounds, organophosphine precious metal catalysts and pharmaceutical intermediates research and development, production and customization. Since its establishment, the company own a young, high-quality and high-tech R & D, production and sales team, has a wealth of catalyst and ligand products research and development, production experience, can quickly develop and produce customer demand products, while can undertake difficult custom synthesis projects. Adhering to the core values of "people-oriented, honest work, harmonious development", the company has always taken "creating value for customers, creating platforms for employees, creating wealth for society" as its mission, and strives to cooperate with all sectors of society to achieve healthy and long-term sustainable development of the company.
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