Thionyl Chloride CAS 7719-09-7
PRODUCT NAME: Thionyl chloride
CAS： 7719-09-7
PURITY: 99%
APPEARANCE: Colorless or yellow liquid
USAGE:Pharmaceutical intermediate(Anti-cancer drugs), Pesticide synthesis, Chlorinating agent
SHELF TIME: 12 Months
Description
About Thionyl chloride cas 7719-09-7
1. Capacity:
About 300 tons per year. Can be mass-produced and has sufficient inventory.
2. Properties:
The Thionyl chloride is colorless or yellow liquid with characteristic pungent smell.
● Miscible with toluene, chloroform, benzene, carbon tetrachloride and ether.
● Reacts violently with water. Incompatible with most common metals, strong reducing agents, strong bases, alcohols, amines.
3. Usages:
Pharmaceutical intermediate(Anti-cancer drugs), Pesticide synthesis, Chlorinating agent
.
Thionyl chloride details
Basic information
| Name： | Thionyl chloride |
| MF： | Cl2OS |
| MW： | 118.97 |
| CAS： | 7719-09-7 |
Appearance
Colorless or yellow liquid
Note:
Reacts violently with water
Packages
Normal package :
1kg/5kg/10kg/bottle
25kg/100kg/drum
For sample:
50g/100g/bottle
shippment
Large order: By sea
For sample: By express
Small order or urgent need: By air
Product Quality Standard
Product chemical properties:
| Melting point | -105 °C |
| Boiling point | 79 °C(lit.) |
| density | 1.64 g/mL at 20 °C |
| vapor density | 4.1 (vs air) |
| vapor pressure | 97 mm Hg ( 20 °C) |
| refractive index | n20/D 1.518(lit.) |
| Fp | 105°C |
| storage temp. | Store at RT. |
| form | Liquid |
Specification sheet:
| Test | Specification |
| Titration with AgNO3 | ≥ 99.0 % |
| Infrared Spectrum | Passes Test |
Advantages
1.Adavantages of Thionyl chloride
● Highly efficient chlorination capacity
It can react efficiently with alcohol, carboxylic acid, acid anhydride and other organic compounds containing hydroxyl, converting hydroxyl into chlorine atoms, which is a very effective chlorination agent. For example, in the reaction of alcohol to chlorinated hydrocarbons, the reaction rate is fast and the conversion rate is high.
● The reaction is irreversible
When preparing chloroalkanes from alcohols, the reaction intermediate product chlorinated sulfite is heated automatically decomposed into hydrogen chloride and sulfur dioxide, both of which are gases and will be removed from the reaction system, making the reaction irreversible, which is conducive to the reaction in the direction of product generation, and can obtain higher product yield, and ultimately no other by-products, the separation and purification of products is particularly convenient.
2. Advantages of our production of Thionyl chloride
● Advanced production technology
Our company adopts advanced production technology and equipment to ensure the production process of Thionyl chloride is efficient and stable. We have a professional R & D team, constantly optimize the production process, improve product quality and purity.
● Rich product line
Our company not only produces thionyl chloride, but also develops a series of sulfoxide chloride derivatives and supporting products according to market demand. These products are widely used in pesticide, medicine, dyes and other fields to provide customers with more comprehensive solutions.
Products Usages
usages of Thionyl Chloride CAS 7719-09-7
Acid Chlorides series products from Shandong Sparrow Chemical CO.,LTD
Pharmaceutical intermediates
(Anti-cancer drugs)
Thionyl chloride plays an important role in the synthesis of anticancer drugs and can be used to synthesize many anticancer drugs:
1. Prednisoline/Prednisoline mustard:
Thionyl can be directly used as the raw material of these anticancer drugs and participate in their synthesis process.
2. Sorafenib:
Methyl 4-chloro-2-picolinate is a key intermediate in the preparation of sorafenib. Thionyl chloride reacts with 2-pyridinic acid to form 4-chloro-2-pyridinyl chloride hydrochloride, and then reacts with methanol to form 4-chloro-2-pyridinic acid methyl ester, thereby indirectly synthesizing sorafenib, an anticancer drug.
Pesticide synthesis
The chlorine atoms of thionyl chloride can replace functional groups such as hydroxyl and sulfhydryl groups in pesticide molecules to form chlorides, thereby changing the chemical structure and properties of pesticide molecules and enhancing their insecticidal, bactericidal or herbicidal activities.
1.Inabenfide
It is used to improve the lodging resistance of crops and help crops grow more stable.
2. S-5439
A highly effective, broad-spectrum insecticide with contact and stomach toxicity and a quick knockout effect on pests.
Chlorinating agent
1. Chlorinated hydrocarbons
Alcohols react with thionyl chloride to first generate chlorosulfonic acid ester, and chlorosulfonic acid ester is further decomposed with thionyl chloride or the diester sulfite generated when alcohol is excessive, and the corresponding chlorinated hydrocarbons can be obtained. For example, ethanol reacts with thionyl chloride to produce chloroethane.
2. Chlorophenol
Phenol reacts with thionyl chloride to obtain chlorophenol. Chlorophenol is an important organic compound, which has bactericidal and antiseptic properties, and is widely used in pesticide, dye and medicine industry.
Related Product Introduction
Shandong Sparow Chemical is one of the leading enterprises focusing on the production of high-quality chemical raw materials. We are committed to providing our customers with a range of innovative, efficient and environmentally friendly chemical feedstock solutions to meet the needs of different industries.
As an important member of the chemical industry, we continue to invest in research and development to promote technological innovation and product upgrades. Our research and development team has rich experience and expertise, and is committed to developing new products and technologies with independent intellectual property rights to meet the changing market and customer needs.
By choosing Shandong Sparrow Chemical, you are choosing high quality, environmental protection, innovation and excellent service.
Related Products:
| Product Name | CAS NO. |
| Phosgene | 75-44-5 |
| Phosphorus oxychloride | 10025-87-3 |
Usage:
In the treatment of cancer, drug therapy is a very important link, and the use of effective anti-cancer drugs can help patients get a longer survival time and have the hope of survivingother fragrances, increase the attractiveness of products.
| Product Name | CAS NO. |
| Phosphorus pentachloride | 10026-13-8 |
| Oxalyl chloride | 79-37-8 |
| Sulfuryl chloride | 7791-25-5 |
Usage:
Chlorination agent is a reagent that can promote the increase of chlorine atoms in organic matter through chlorination reaction
Products Shipment
Shipment
01
International express
02
By sea
03
By air
04
By railway
How to start order?
Contact information:
Melanie Yin
Phone: +8615662727073
Email: export012@sparrowchemical.com
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